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Trying to Get the Smell of Pee Out of Mattress

Hello we had some house guess a few weeks ago and there 8 year old son was staying in my sons bed and wetting it every night and never said any thing to us about it. And know I am trying every thing to get the smell out of it. We have tried shampooing it and I even got some stuff from the pet store that you poor on it to get rid of the smell. I would really like to save my mattress it cost a pretty penny but I also cant have my son sleeping on this mattress that smells. Any help would be great thanks