HI H., I feel you on the difficulties with preemies. My twins were born at 28 weeks, and they spent 3 months in the NICU at Banner Desert. I think the thing that helped me the most when they first came home was trying to keep to the very strict schedule that the NICU had them on. Feeding and diaper change every three hours, and take no more than 30 minutes to do this. It is kind of hard to stick to, especially if you are out doing any running around, or now with the holidays coming up and family coming into town (or you going to them, whatever your case may be), but just try to stick to it. It will be very hard to get back into, but if you can tough it out for a week or so, it will just become habit for him. If he knows that he will be fed every three hours, his body will eventually not be hungry until that time, and he won't fuss if he does get hungry, because he will know that he is going to be fed soon. Also, make sure that you are changing his diaper every three hours, even if it is only pee, otherwise he will be very susceptible to diaper rash. My best friend also used to change her son only after a poop, and he had very bad diaper rash all the time. I finally had her try changing every three hours, and he hasn't had one rash in the last three months. And make sure to use a wipe every time. I know it sounds silly, but even pee has bacteria in it that needs to be wiped away. That could be part of why he is so colicky. How would you feel if you had to stay in a dirty diaper? One more thing... since he does have reflux, when you lay him down to sleep, you might try putting him in a Boppy. It says right on the Boppy "not intended for sleep", however, I found that it helped my daughter (who was on Reglan for two months until I discovered this trick). If you do decide to put him in it though, you do so at your own risk, and should check on him often until you know how he will react. I know that it all seems daunting right now, but you will get through it. Schedule is the key. Good luck!!