From what I understand, impetigo is a sort of secondary infection to something else. I had this as a child...really bad...from about age 4 to age 9 consistently. I only had it in one place, but it would come back repeatedly in the same place. Even as an adult, I still get it about once every other year. I get it right above my top lip on the left side beside of my nose. About the area that creases when you smile. As a matter of fact, I got it so many times, I have a slight scar on my face and my skin is nub in the little area. The doctor told my mother that I had contracted it from a Strep type virus that had went around my daycare. Whatever virus that I contracted stayed with me, and it became constant in my blood stream. Everytime my immune system would be weakened in the slightest way, it would come back. He (dr.) said it was like carrying a herpes simplex type virus (cold sore virus) that appeared on the body instead of the mouth. Anything that is herpes related will blister. I remember that my mother would apply peroxide to my skin and slightly rub until the blister would pop, then use Neosporin (sp?) several times a day. She would do this (while I was kicking and screaming...haha...poor lady!) every day until it was gone. I just thought I'd tell you about my first hand experience with this "sickness". Hope this helps even a little.