I can only speak for myself, but my first pregnancy was a singleton (1 baby), my second pregnancy was with triplets, and I am now pregnant for the third time with one. With all of my pregnancies, I had different symptoms, tiredness, constipation, heartburn, reflux, feeling 'green'. All were different, but my multiples pregnancy didn't lead me to think anything was different, until I had my ultrasound...then I about fell off the exam table. All are healthy, 9 yo, 7 yo triplets, and baby due in April'10. Good luck to you!