I had 3 cats when my son was born, and I didn't have any trouble. My concern was that cats sleeping in the crib. I knew they wouldn't deliberately smother him, but one of my cats is fat and clumsy (sad, but true). I could see her jumping in the crib and accidentally hitting my Alex. So, I bought a cat cover for the crib. It worked great! It's just a domed netting over the crib. The cats stayed out of the crib, and I could keep the doors open in case Alex cried at night. (Besides, it kept him in the crib as he got older. I never had to worry about him climbing out of the crib!) Something to think about.