I have had 4 surgeries for endometriosis and my first was when I was 18 and I am now 28 and a mother to a beautiful 13 month old daughter. I have struggled with endo for years and researched everything that could possibly help. The Depot Lupron injections have some pretty serious side effects that you should think about. It puts you into a menopausal type state, with weight gain, mood swings etc. After my research I decided to not do Lupron because I did not see the point in trading one problem for the next. What has helped me the most is to have a laproscopic surgery where my doctor scraped out all the endometriosis lesions she could find, then I take a constant dose of birth control. Currently, I am on Yaz and I do not take the sugar pills. This in turn keeps me from having my period. If you you don't have a period, then the endometriosis lesions are less likely to grow since you are not cycling. I know some say you need to have your period, but I have had trouble since I was 14 years old with periods every 2 weeks for 7 days. I want to have more kids and I feel like, along with my doctor, this is the best option for now, to keep it under control. When I was 22 I did go to the Center for Endometriosis Care in Atlanta, GA where I had my 3rd surgery and started the constant birth control regimen after that. Once we decided to have a baby, I did go off the birth control and had one more surgery to clean up the endometriosis that had formed over 4 years. This was the longest I had made it without and endo surgery for a while. I know this may sound confusing, but I truly believe in the constant birth control instead of Lupron. Please let me know if you have questions. I know the pain and frustration that comes with endometriosis.